三、主要科研工作与成绩 承担课题 2017年国家自然科学基金：AhR调控血管微环境对血管平滑肌的影响及其在内皮损伤修复中的作用 2019年上海市科委生物医药领域科技支撑项目🪤：新型可降解弹簧圈的研发 2020年长海医院234攀登计划：随机、开放🍩、肝素对照以评价比伐芦定用于破裂动脉瘤患者弹簧圈栓塞术中抗凝有效性和安全性的临床研究
学术论文 1.Fang,X., R. Zhao, K. Wang, Z. Li, P. Yang, Q. Huang, Y. Xu, B. Hong,and J. Liu. "Bone Marrow-Derived Endothelial Progenitor CellsAre Involved in Aneurysm Repair in Rabbits." [In eng]. J ClinNeurosci 19, no. 9 (Sep 2012): 1283-6. 2.Huai,W., R. Zhao, H. Song, J. Zhao, L. Zhang, L. Zhang, C. Gao, L. Han,and W. Zhao. "Aryl Hydrocarbon Receptor Negatively RegulatesNlrp3 Inflammasome Activity by Inhibiting Nlrp3 Transcription."[In eng]. Nat Commun 5 (Aug 20 2014): 4738. 3.Li,Z., R. Zhao, X. Fang, Q. Huang, and J. Liu. "RecombinantHuman Sdf-1alpha Administration Accelerates Aneurysm NeckReendothelialization in Rabbit Saccular Aneurysm after FlowDiverter Treatment." [In eng]. Acta Biochim Biophys Sin(Shanghai) 49, no. 3 (Mar 1 2017): 246-53. 4.Li,Z., R. Zhao, X. Fang, J. Zhou, G. Jiang, Q. Huang, and J. Liu."Amd3100 Accelerates Reendothelialization of Neointima inRabbit Saccular Aneurysm after Flow Diverter Treatment." [Ineng]. World Neurosurg 107 (Nov 2017): 416-23. 5.Li,Z. F., X. G. Fang, P. F. Yang, Q. H. Huang, W. Y. Zhao, C. Liang,R. Zhao, and J. M. Liu. "Endothelial Progenitor CellsContribute to Neointima Formation in Rabbit Elastase-InducedAneurysm after Flow Diverter Treatment." [In eng]. CNSNeurosci Ther 19, no. 5 (May 2013): 352-7. 6.Liang,C., H. Feng, B. Q. Deng, Z. F. Li, Q. H. Huang, W. Zhao, W. Y.Zhao, et al. "Decreased Levels and Function of CirculatingEndothelial Progenitor Cells in Unruptured Intracranial SaccularAneurysm Patients." [In eng]. Neurol Sci 35, no. 1 (Jan2014): 23-8. 7.Song,H., B. Deng, C. Zou, W. Huai, R. Zhao, and W. Zhao. "Gsk3betaNegatively Regulates Lps-Induced Osteopontin Expression ViaInhibiting Its Transcription." [In eng]. Scand J Immunol 81,no. 3 (Mar 2015): 186-91. 8.Tang,H., Y. Luo, Q. Zuo, C. Wang, Q. Huang, R. Zhao, and J. Liu."Current Understanding of the Molecular Mechanism betweenHemodynamic- Induced Intracranial Aneurysm and Inflammation."[In eng]. Curr Protein Pept Sci 20, no. 8 (2019): 789-98. 9.Wang,C., R. Zhao, X. Chang, Q. Li, Y. Fang, B. Hong, Y. Xu, Q. Huang,and J. Liu. "Feasibility and Midterm Outcomes of EndovascularEmbolization for True Posterior Communicating Artery Aneurysms."[In eng]. Neuroradiology 61, no. 10 (Oct 2019): 1191-98. 10.Xue,G., H. Tang, P. Liu, Q. Zuo, P. Yang, Y. Zhou, Q. Li, et al."Safety and Long-Term Efficacy of Stent-Assisted Coiling forthe Treatment of Complex Posterior Cerebral Artery Aneurysms."[In eng]. Clin Neuroradiol (Aug 15 2019). 11.Zhao,K., R. Zhao, X. Yang, S. Guan, G. Liang, H. L. Wang, D. Wang, etal. "Predictors of Unfavorable Outcome in Stent-AssistedCoiling for Symptomatic Unruptured Intracranial SpontaneousVertebral Artery Dissecting Aneurysms (Uis-Vadas): Results from aMulticenter Study." [In eng]. J Neurointerv Surg (Nov 92021). 12.Zhao,K. J., R. Zhao, Q. H. Huang, Y. Xu, B. Hong, Y. B. Fang, Q. Li, etal. "The Interaction between Stent(S) Implantation, PicaInvolvement, and Immediate Occlusion Degree Affect SymptomaticIntracranial Spontaneous Vertebral Artery Dissection Aneurysm(Sis-Vada) Recurrence after Reconstructive Treatment withStent(S)-Assisted Coiling." [In eng]. Eur Radiol 24, no. 9(Sep 2014): 2088-96. 13.Zhao,R., G. Duan, P. Yang, T. Li, S. Guan, H. Yang, Z. Zhao, et al."Endovascular Aneurysm Treatment with the Numen CoilEmbolization System: A Prospective Randomized ControlledOpen-Label Multicenter Noninferiority Trial in China." [Ineng]. World Neurosurg (Dec 11 2021). 14.Zhao,R., W. Li, B. Hong, Y. Xu, W. Zhao, P. Yang, Q. Huang, and J. Liu."The Safety and Efficacy of Stenting in the Treatment ofComplex Posterior Cerebral Artery Aneurysms: A Seven-Case Reportand Literature Review." [In eng]. Clin Neuroradiol 23, no. 3(Sep 2013): 175-87. 15.Zhao,R., J. Liu, S. McComas, J. Guo, and G. Girdhar. "In-VitroPliability Assessment of Embolization Coils for IntracranialAneurysm Treatment." [In eng]. J Neurol Sci 406 (Nov 152019): 116432. 16.Zhao,R., J. Shen, Q. H. Huang, J. H. Nie, Y. Xu, B. Hong, P. F. Yang,W. Y. Zhao, and J. M. Liu. "Endovascular Treatment ofRuptured Tiny, Wide-Necked Posterior Communicating ArteryAneurysms Using a Modified Stent-Assisted Coiling Technique."[In eng]. J Clin Neurosci 20, no. 10 (Oct 2013): 1377-81. 17.赵瑞👦🏽，路智文，邓晓东，邹超，左乔💃，赵开军，戴冬伟，方亦斌，李强☎️，黄清海🧙🏿♀️🕑，洪波，许奕，刘建民，创伤性颈内动脉颅内段假性动脉瘤的血管内治疗,第二军医大学学报. 2021,42(02) 18.赵瑞，吕楠🧑🏿🎄，周宇，李强，方亦斌，杨鹏飞，黄清海🍿，洪波，许奕，刘建民，血流导向装置治疗椎动脉夹层动脉瘤的单中心临床经验，中华神经外科杂志. 2019,35(09) |
